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Dr. Devashish Sengupta

Dr. Devashish Sengupta

Assistant Professor

Department of Chemistry

Email: devashishsg@gmail.com

Phone: 9954055466

Personal Page

Education:

Ph.D.  University of Sydney, (Australia) 2007

M. Sc. (specialization: Organic Chemistry, NEHU, 1993

B.Sc. St. Edmunds College, 1992

Teaching & Research Experience:

Assistant Professor:  2008-2021

Administrative Experience:

  1. General Secretary Assam University Teachers’ Association (AUTA) – 2016-2018, 2019-2021.
  2. Member of Admission Committee AUS (2017)

Conference/Seminar Organized:

  1. Convener: International Webinar on “Antiviral Drug Discovery: Creation of an Armory for the Present and Future Pandemics”, August, 2020.
  2. Jt. Coordinator: International Conference 2018 held at the dept. of Chemistry AUS.

Research Interests:

  1. Chemical Biology of water-soluble photosensitizers involving tetrapyrrolic macrocycles (porphyrins, corroles, phthalocyanines etc.), fullerenes, and quinazolines.
  2. Applications of the synthesized photosensitizers under biomolecular prospects considering both cancer and antimicrobial Photodynamic Therapy (PDT).
  3. Applications of the synthesized compounds as anti-viral (especially anti HIV-1), anti-bacterial, and anti-fungal agents.

Research Guidance:

PhD Students:

  1. Synthesis and characterization of organic photovoltaic solar materials and four-ring bent core liquid crystals., Dr. Kalpana Upadhyaya, 2015
  2. synthesis and Characterization of 3d Metallomesogens, Dr. Ramesh Panyam, 2017
  3. Water-soluble, meso-substituted, Free-base and Metallated Thiophenium and/or Pyridinium and/or Indole Derivatives of Porphyrin: Their Role as Photosensitizers, Dr. Zeaul Hoque Mazumder, 2018

M.Sc.  Students:

Total: 21 students (from year .2015 to 2020)

Research Project:

  1. Nitronium and Sulphonium Containing Monomeric and Dimeric, Free Base and Metalized Porphyrin-Carbon NPs: Synthesis, Characterization, and Their Structure Activity Relationships in Interpreting Their Roles as Selective Photosensitizers in Photodynamic Therapy (PDT). Amount Sanctioned: INR 81,69500/-(Rupees Eighty One Lakhs Sixty Nine Thousand Five Hundred Only)
  2. Nanoassisted C60 -Pyrimidine Derivatives: Their Synthesis, Characterization, Neuroprotective and Antiviral Activities. Amount Sanctioned: INR 90,87,000/- (Ninety Lakh and Eighty Seven Thousand only)
  3. Study of Water-Soluble (C70 -and C60-) Fullerene-Porphyrin Dyads as Inhibitors of Human Immunodeficiency Virus (HIV): Synthesis, Characterization and Anti-HIV Activity. Amount Sanctioned: INR 79,99,600/- (Seventy nine Lakh, Ninty nine Thousand and six hundred only)

List of Publications (last 5 years):

  1. Sharma, D., Mazumder, Z. H., Sengupta, D., Mukherjee, A., Sengupta, M., Das, R. K., … & Jha, T. (2021). Cancer photocytotoxicity and anti-inflammatory response of cis-A 2 B 2 type meso-p-nitrophenyl and p-hydroxyphenyl porphyrin and its zinc (ii) complex: a synthetic alternative to the THPP synthon. New Journal of Chemistry,2021, 45(4), 2060-2068.
  2. Mazumder, Z. H., Sharma, D., Sengupta, D., Mukherjee, A., Boruah, J. S., Basu, S., … & Jha, T. (2020). Photodynamic activity attained through the ruptured π-conjugation of pyridyl groups with a porphyrin macrocycle: synthesis and the photophysical and photobiological evaluation of 5-mono-(4-nitrophenyl)-10, 15, 20-tris-[4-(phenoxymethyl) pyridine]-porphyrin and its Zn (ii) complex. Photochemical & Photobiological Sciences, 2020, 19(12), 1776-1789.
  3. Mazumdar, Z. H., Sharma, D., Mukherjee, A., Basu, S., Shukla, P. K., Jha, T., & Sengupta, D. (2020). meso-Thiophenium Porphyrins and Their Zn (II) Complexes: A New Category of Cationic Photosensitizers. ACS Medicinal Chemistry Letters, 2020, 11(10), 2041-2047.
  4. Sengupta, D., Timilsina, U., Mazumder, Z. H., Mukherjee, A., Ghimire, D., Markandey, M., … & Gaur, R. (2019). Dual activity of amphiphilic Zn (II) nitroporphyrin derivatives as HIV-1 entry inhibitors and in cancer photodynamic therapy. European journal of medicinal chemistry, 2019, 174, 66-75.
  5. Sengupta, D., Mazumdar, Z. H., Mukherjee, A., Sharma, D., Halder, A. K., Basu, S., & Jha, T. (2018). Benzamide porphyrins with directly conjugated and distal pyridyl or pyridinium groups substituted to the porphyrin macrocycles: Study of the photosensitising abilities as inducers of apoptosis in cancer cells under photodynamic conditions. Journal of Photochemistry and Photobiology B: Biology, 2018, 178, 228-236.